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RECENT Artery Conversations

Swing Out vs Fixed Angle Rotor Centrifuge
MAY.03.2019

I know there are several advantages to swing out rotor centrifuges but does anyone know of any tests that require that a tube be processed in a swing out centrifuge before being sent to the lab? Join the conversation.

HbA1c Mainline Chemistry or HPLC
MAY.03.2019

Currently we perform A1C testing using Biorad Variant HPLC Analyzer, and using the Biorad D10 analyzer for when we have interference from Hb Variants. We are looking to update and are considering running A1C on our mainline Chemistry System. I have concerns about doing that because any interference from Hb variants are not detected using mainline chemistry systems and I am concerned about reporting false results. What is the opinion on running A1C using a non-HPLC method?

Pediatric Celiac Testing
MAY.03.2019

I can recall several discussions about celiac testing over the years here in the Artery...but not one specifically about testing in the ped's population. Our ped's gastroenterologists maintain that deamidated gliadin peptide IgG rather than IgA should be tested if tissue transglutaminase IgA is negative. Can anyone out there help me with the literature search and/or discussion for this? I get (of course) that IgA-deficient patients would produce IgG - but why would we start with IgA and reflex to IgG for a different marker, if we know the total IgA level is sufficientGive your advice.

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